HCID 18472611, compound → HCID 18472303, compound

HRID 2228176Notes

Reaction equation

HRID 2228176 reaction equation
[N+:1]([C:4]1[CH:16]=[CH:15][C:7]([CH2:8][P:9](=[O:14])([CH2:12][CH3:13])[CH2:10][CH3:11])=[CH:6][CH:5]=1)([O-])=O>C(O)C.[Pd]>[NH2:1][C:4]1[CH:16]=[CH:15][C:7]([CH2:8][P:9](=[O:14])([CH2:10][CH3:11])[CH2:12][CH3:13])=[CH:6][CH:5]=1

Participants

4

Reactant 1

HCID 18472611HCID 18472611, compound

Product 1

HCID 18472303HCID 18472303, compoundYield 99.6%

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

A mixture of 4-nitrobenzyldiethylphosphine oxide (0.4 g) and 10% Pd-C (0.06 g) in ethanol (10 ml) was vigorously stirred under hydrogen atmosphere for 16 hours, and the Pd-C was filtered off. The filtrate was concentrated under reduced pressure to give 4-aminobenzyldiethylphosphine oxide (349 mg) as brown oil.

Workup

  1. filtrationthe Pd-C was filtered off
  2. concentrationThe filtrate was concentrated under reduced pressure

Sources & evidence

ORD record
ord-34493b6d7d434951b76b0f17a6dac3fe
Source dataset
uspto-grants-2002_07
Patent number
US06413947B1

Reaction notes

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