HCID 178527015, compound → HCID 178507650, compound

Participants

Reaction Steps

A mixture of 1—(4-nitrobenzyl)phosphorane-1-oxide (1.80 g) and 10% Pd-C (0.2 g) in ethanol (30 ml) was vigorously stirred under hydrogen atmosphere for 24 hours, and the catalyst was filtered off. The filtrate was concentrated and purified with column chromatography (ethanol/ethyl acetate=1:2) and recrystallized from ethanol-diethylether to give 1—(4-aminobenzyl)phosphorane-1-oxide (0.90 g) as colorless crystals.

Provenance & Evidence