Triphenylphosphine → HCID 53637259, compound

Participants

Reaction Steps

A 50 ml reaction flask was charged with 1-butyne-3-ol and a catalytic amount of bis(1,5-cyclooctadiene)-di-Rh(I)-dichloride and triphenylphosphine under an inert atmosphere. Triethylsilane was slowly added to the reaction flask through a dropping funnel. The reaction mixture was stirred at room temperature for 72 hours and then concentrated at the rotary evaporator. The product was chromatographed through SiO2 in a hexane:ethylacetate solution (95:5 to 70:30) to yield 86% of a yellow liquid. Purity according to gas chromatography was 96% trans and 3.4% cis product.

Provenance & Evidence