Maleic Anhydride → 2-Hydroxyethyl oxabicyclo[2,2,1]hept-5-ene-2-carboxylate t-butyl 5-norbornene-2-carboxylate 5-norbornene-2-carboxylic acid maleic anhydride

HRID 2228363노트

반응식

HRID 2228363 반응식
[CH:1]12[CH2:7][CH:4]([CH:5]=[CH:6]1)[O:3][CH:2]2[C:8]([O:10][CH2:11][CH2:12][OH:13])=[O:9].[CH:14]12[CH2:20][CH:17]([CH:18]=[CH:19]1)[CH2:16][CH:15]2[C:21]([O:23][C:24]([CH3:27])([CH3:26])[CH3:25])=[O:22].[CH:28]12[CH2:34][CH:31]([CH:32]=[CH:33]1)[CH2:30][CH:29]2[C:35]([OH:37])=[O:36].[C:38]1(=[O:44])[O:43][C:41](=[O:42])[CH:40]=[CH:39]1>O1CCCC1>[CH:1]12[CH2:7][CH:4]([CH:5]=[CH:6]1)[O:3][CH:2]2[C:8]([O:10][CH2:11][CH2:12][OH:13])=[O:9].[CH:14]12[CH2:20][CH:17]([CH:18]=[CH:19]1)[CH2:16][CH:15]2[C:21]([O:23][C:24]([CH3:27])([CH3:26])[CH3:25])=[O:22].[CH:28]12[CH2:34][CH:31]([CH:32]=[CH:33]1)[CH2:30][CH:29]2[C:35]([OH:37])=[O:36].[C:41]1(=[O:42])[O:43][C:38](=[O:44])[CH:39]=[CH:40]1

참가 물질

6

반응물 4

HCID 7923Maleic AnhydrideHCID 789495-Norbornene-2-carboxylic acidHCID 15607334Bicyclo[2.2.1]hept-5-ene-2-carboxylic acid, 1,1-dimethylethyl esterHCID 701791922-Hydroxyethyl oxabicyclo[2,2,1]hept-5-ene-2-carboxylate

생성물 1

HCID 867583182-Hydroxyethyl oxabicyclo[2,2,1]hept-5-ene-2-carboxylate t-butyl 5-norbornene-2-carboxylate 5-norbornene-2-carboxylic acid maleic anhydride수율 290.9%

시약·촉매·용매 1

HCID 8028Tetrahydrofuran용매

실험 절차

2-hydroxyethyl oxabicyclo[2,2,1]hept-5-ene-2-carboxylate (0.1 mol), t-butyl 5-norbornene-2-carboxylate (0.85 mol), 5-norbornene-2-carboxylic acid (0.05 mol) and maleic anhydride (1 mol) were dissolved in tetrahydrofuran solvent (200 g). Thereto, 2,2-azobisisobutyonitrile (5.84 g) was added, and the solution was mixed. The solution was polymerized at a temperature of 67° C. in a nitrogen atmosphere for 10 hours. After the polymerization reaction was completed, the polymer was precipitated in an ethyl ether solvent, then was dried in a vacuum to obtain the pure title polymer (89.4 g) having a molecular weight of approximately 6700. (yield: 31%, purity: 99.9%).

후처리

  1. additionthe solution was mixed
  2. customThe solution was polymerized at a temperature of 67° C. in a nitrogen atmosphere for 10 hours
  3. customAfter the polymerization reaction
  4. customthe polymer was precipitated in an ethyl ether solvent
  5. customwas dried in a vacuum

출처 및 근거

ORD 기록
ord-10d70a71be034078aeebb35725043f86
출처 데이터셋
uspto-grants-2002_07
특허 번호
US06416926B1

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