Hydroquinone → HCID 18469780, compound

Participants

Reaction Conditions

Reaction Steps

Next, into a flask of 200 ml capacity fitted with a stirrer and cooling tube, there were introduced 15.7 g of 1-(2-chloroethyl)-5-methoxyindole, 18.6 g of potassium methacrylate, 6.2 g of potassium iodide, 40 ml of N,N-dimethylsulfoxide, and a small amount of hydroquinone. They were heated to 100° C., and stirred for 2.5 hours. After completion of the reaction, the insoluble material was removed by infiltration, and concentration was performed under reduced pressure. Further, this reaction mixture was purified by column chromatography using silica gel, to obtain a 16.8 g of 1-(2-methacryloyloxyethyl)-5-methoxyindole.

Provenance & Evidence