tert-Butyl (3-aminopropyl)carbamate → HCID 18470608, compound

Participants

Reaction Steps

N-t-butyloxycarbonyl-1,3-diaminopropane (574 mg, 3.29 mmol) and 3-(2-chloro-6-fluorophenyl)-5-methylisoxazol-4-oyl chloride (903 mg, 3.29 mmol) were converted to 1.36 g of the title compound by the procedure of Preparation 1. (100%). EA calculated for: C19H23N3O4ClF: C, 55.41; H, 5.63; N, 10.20. Found: C, 55.17; H, 5.71; N, 9.99. MS(IS) m/z 412 (M+).

Provenance & Evidence