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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 222853Generated: October 26, 2026

P-Anisidine → HCID 67528647, compound

https://huagongshe.com/reaction/222853

Reaction equation

Participants

RoleNameHCIDCharge
ReactantP-AnisidineHCID 7732—
Reactant2-Fluoro-1-methyl-3-nitrobenzeneHCID 13470957—
ReactantPotassium tert-butoxideHCID 23665647—
SolventDimethyl SulfoxideHCID 679—
ProductHCID 67528647HCID 67528647—

Reaction Steps

The product (487 mg) is obtained according to the method of stage 1 of Example 4, by using 1 g of 2-fluoro-3-methyl-nitrobenzene and 1.19 g of 4-methoxyaniline in the presence of 1.16 g of potassium tert-butanolate in 9 mL of DMSO.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08207373B2
Source datasetuspto-grants-2012_06
ORD IDord-9209797cbcbf4d25bd8c9c78cc271804
Source noteuspto-grants-2012_06