2-Thiopheneboronic acid → HCID 18470702, compound

HRID 2228619Notes

Reaction equation

HRID 2228619 reaction equation
[C:1]([C:4]1[C:8]([CH3:9])=[C:7]([C:10]2[CH:15]=[CH:14][N:13]=[CH:12][CH:11]=2)[NH:6][C:5]=1Br)(=[O:3])[CH3:2].[S:17]1[CH:21]=[CH:20][CH:19]=[C:18]1B(O)O>>[C:1]([C:4]1[C:8]([CH3:9])=[C:7]([C:10]2[CH:15]=[CH:14][N:13]=[CH:12][CH:11]=2)[NH:6][C:5]=1[C:18]1[S:17][CH:21]=[CH:20][CH:19]=1)(=[O:3])[CH3:2]

Participants

3

Reactant 2

HCID 27339602-Thiopheneboronic acidHCID 18470740HCID 18470740, compound

Product 1

HCID 18470702HCID 18470702, compound

Procedure

The title compound was prepared from 3-acetyl-2-bromo-4-methyl-5-(4-pyridyl)-1H-pyrrole according to the procedure of Example 46 using 2-thienylboronic acid instead of 4-pyridylboronic acid in step 3.

Sources & evidence

ORD record
ord-900cf400aa59498397d9b127769a9001
Source dataset
uspto-grants-2002_07
Patent number
US06417202B1

Reaction notes

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