2,2-Diphenylethyl methanesulfonate → [[2-(2,2-Diphenylethyl)thio-8H-indeno[1,2-d]thiazol-7-yl)oxy]acetic Acid

HRID 2228680Notes

Reaction equation

HRID 2228680 reaction equation
[SH:1][C:2]1[S:3][C:4]2[CH2:13][C:12]3[C:11]([O:14][CH2:15][C:16]([O:18]CC)=[O:17])=[CH:10][CH:9]=[CH:8][C:7]=3[C:5]=2[N:6]=1.CS(O[CH2:26][CH:27]([C:34]1[CH:39]=[CH:38][CH:37]=[CH:36][CH:35]=1)[C:28]1[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=1)(=O)=O>>[C:28]1([CH:27]([C:34]2[CH:35]=[CH:36][CH:37]=[CH:38][CH:39]=2)[CH2:26][S:1][C:2]2[S:3][C:4]3[CH2:13][C:12]4[C:11]([O:14][CH2:15][C:16]([OH:18])=[O:17])=[CH:10][CH:9]=[CH:8][C:7]=4[C:5]=3[N:6]=2)[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=1

Participants

3

Reactant 2

HCID 117478202,2-Diphenylethyl methanesulfonateHCID 178472950HCID 178472950, compound

Product 1

HCID 53962557[[2-(2,2-Diphenylethyl)thio-8H-indeno[1,2-d]thiazol-7-yl)oxy]acetic AcidYield 37%

Procedure

Using ethyl [(2-mercapto-8H-indeno[1,2-d]thiazol-7-yl)oxy]acetate and 2,2-diphenylethyl methanesulfonate, the procedure of Example 1 was otherwise repeated to synthesize the title compound. Yield 37%.

Sources & evidence

ORD record
ord-717f1ab18e0949d8b4954f7a6c052126
Source dataset
uspto-grants-2002_07
Patent number
US06417213B2

Reaction notes

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