HCID 22565374, compound → HCID 53754615, compound

HRID 2228716Notes

Reaction equation

HRID 2228716 reaction equation
[SH:1][C:2]1[S:3][C:4]2[CH2:14][CH2:13][C:12]3[C:7](=[CH:8][CH:9]=[CH:10][C:11]=3[O:15][CH2:16][C:17]([O:19]CC)=[O:18])[C:5]=2[N:6]=1.[F:22][C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][C:24]=1[CH:29](Br)[C:30]1[CH:35]=[CH:34][CH:33]=[CH:32][C:31]=1[F:36]>>[F:22][C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][C:24]=1[CH:29]([C:30]1[CH:35]=[CH:34][CH:33]=[CH:32][C:31]=1[F:36])[S:1][C:2]1[S:3][C:4]2[CH2:14][CH2:13][C:12]3[C:7](=[CH:8][CH:9]=[CH:10][C:11]=3[O:15][CH2:16][C:17]([OH:19])=[O:18])[C:5]=2[N:6]=1

Participants

3

Reactant 2

HCID 22565374HCID 22565374, compoundHCID 178472952Ethyl[(2-mercapto-4,5-dihydronaphtho[1,2-d]thiazol-6-yl)oxy)acetate

Product 1

HCID 53754615HCID 53754615, compoundYield 58%

Procedure

Using ethyl [(2-mercapto-4,5-dihydronaphto[1,2-d]thiazol-6-yl)oxy]acetate and bis(2-fluorophenyl)methylbromide, the procedure of Example 63 was otherwise repeated to synthesize the title compound. Yield 58%.

Sources & evidence

ORD record
ord-2fee3d24d42943049c9f914f4b5e2eb9
Source dataset
uspto-grants-2002_07
Patent number
US06417213B2

Reaction notes

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