HRID2228947

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID13299492

未命名化合物

HCID22180413

未命名化合物

PRODUCTS

生成物

结构：COc1ccc(C(CCN2CCN(c3ccc4c(c3)C(=O)N(C3CCCCC3)C4)CC2)c2ccc(OC)cc2)cc1

HCID18510924

未命名化合物

收率 59.8%

PROCEDURE

实验过程

In the same manner as in Example 38, the title compound (52 mg) was prepared from the compound (47 mg) obtained in step (e) of Example 1 and the compound (110 mg) obtained in step (b).

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-beac72211c4c4b4ca1e25710de9b4f83
来源数据集: uspto-grants-2002_07
DOI: 10.6084/m9.figshare.5104873.v1
专利: US06417362B1
来源说明: uspto-grants-2002_07

反应 SMILES

[CH:1]1([N:7]2[CH2:15][C:14]3[C:9](=[CH:10][C:11]([N:16]4[CH2:21][CH2:20][NH:19][CH2:18][CH2:17]4)=[CH:12][CH:13]=3)[C:8]2=[O:22])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[CH3:23][O:24][C:25]1[CH:30]=[CH:29][C:28]([CH:31]([C:35]2[CH:40]=[CH:39][C:38]([O:41][CH3:42])=[CH:37][CH:36]=2)[CH2:32][CH:33]=O)=[CH:27][CH:26]=1>>[CH:1]1([N:7]2[CH2:15][C:14]3[C:9](=[CH:10][C:11]([N:16]4[CH2:17][CH2:18][N:19]([CH2:33][CH2:32][CH:31]([C:28]5[CH:27]=[CH:26][C:25]([O:24][CH3:23])=[CH:30][CH:29]=5)[C:35]5[CH:36]=[CH:37][C:38]([O:41][CH3:42])=[CH:39][CH:40]=5)[CH2:20][CH2:21]4)=[CH:12][CH:13]=3)[C:8]2=[O:22])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1