HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylformamide → HCID 15432463, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | Oxalyl chloride | HCID 65578 | — |
| Reactant | HCID 15432462 | HCID 15432462 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | HCID 15432463 | HCID 15432463 | — |
Reaction Steps
1 equivalent of DMF and 1 equivalent of oxalyl chloride are dissolved in acetonitrile at 0°. 1 equivalent of 3-[4-(3-chloro-4-methoxybenzylamino)-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidine-2-yl]propionamide is then added. The mixture is stirred for one hour. After customary working up, 3-[4-(3-chloro-4-methoxybenzylamino)-5,6,7,8-tetrahydro[1]-benzothieno[2,3-d]pyrimidine-2-yl]propionitrile is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06420368B1 |
| Source dataset | uspto-grants-2002_07 |
| ORD ID | ord-7c933bbcb56447e2aa48512326d5ebb2 |
| Source note | uspto-grants-2002_07 |