Isatoic Anhydride → Semicarbazide, 1-(o-aminobenzoyl)-3-thio-

Participants

Reaction Conditions

Reaction Steps

Isatoic anhydride (4.9 g) and thiosemicarbazide (2.8 g) were dissolved in 30 ml of DMF and the resulting mixture was stirred 20 h at 60 to 80° C. The solvent was removed under reduced pressure and the residue was recrystallized from methanol and ethanol to give 2.94 g of 1-(2-aminobenzoyl)thiosemicarbazide.

Provenance & Evidence