HCID 14434140, compound → HCID 69945910, compound

Participants

Reaction Steps

A mixture of (2-naphthyl) [(E)-2-(3-pyridyl)-1-ethenyl]ketone (5.02 g) and palladium black (0.15 g) in AcOH—MeOH—CH2Cl2 (4 ml/50 ml/20 ml) was stirred under hydrogen atmosphere at room temperature for 3 hours. The catalyst was filtered off and the filtrate was concentrated in vacuo. The residue dissolved in ethyl acetate, washed with saturated aqueous NaHCO3 solution and brine, and dried. After removal of the solvent, the residue was recrystallized from hexane-ethyl acetate to give the titled compound (3.48 g) as colorless prisms.

Provenance & Evidence