Acetic Acid → HCID 18467031, compound

Participants

Reaction Steps

A mixture of [(E)-2-(3-pyridyl)ethenyl]-(5,6,7,8-tetrahydronaphthalen-2-yl)ketone (6.32 g), palladium black (150 mg) and acetic acid (3 ml) in MeOH (50 ml) was stirred under hydrogen atmosphere at room temperature for 6 hours. The catalyst was filtered off and the filtrate was concentrated. The residue was dissolved in ethyl acetate, washed with saturated aqueous NaHCO3 solution and brine, and dried. After removal of the solvent, the residue was recrystallized f rom hexane-ethyl acetate to give the titled compound (3.93 g).

Provenance & Evidence