Diisobutylaluminumhydride → HCID 69947098, compound

HRID 2229247Notes

Reaction equation

HRID 2229247 reaction equation
[F:1]/[C:2](=[CH:8]\[C:9]1[CH:18]=[CH:17][C:16]2[C:11](=[CH:12][CH:13]=[CH:14][CH:15]=2)[CH:10]=1)/[C:3](OCC)=[O:4].[H-].C([Al+]CC(C)C)C(C)C>>[F:1]/[C:2](=[CH:8]\[C:9]1[CH:18]=[CH:17][C:16]2[C:11](=[CH:12][CH:13]=[CH:14][CH:15]=2)[CH:10]=1)/[CH2:3][OH:4]

Participants

3

Reactant 2

HCID 21225700DiisobutylaluminumhydrideHCID 86758350HCID 86758350, compound

Product 1

HCID 69947098HCID 69947098, compoundYield 88.7%

Procedure

The reaction of ethyl (Z)-2-fluoro-3-(2-naphthyl)acrylate (3.77 g) with diisobutylaluminum hydride was carried out in a similar manner as described in Reference example 3 to give the titled compound (2.77 g) as a colorless solid.

Sources & evidence

ORD record
ord-826e4ea77dd341c9acca01b72cce9a5e
Source dataset
uspto-grants-2002_07
Patent number
US06420375B1

Reaction notes

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