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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2229387Generated: October 30, 2026

2-amino-N-(-4-cyano-1-methyl-piperidin-4-yl)-3-cyclohexylpropionamide bis hydrochloride salt → HCID 178480340, compound

https://huagongshe.com/reaction/2229387

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-amino-N-(-4-cyano-1-methyl-piperidin-4-yl)-3-cyclohexylpropionamide bis hydrochloride saltHCID 22566339—
Reactant5,6-Difluoro-3-iminoisoindol-1-oneHCID 140432442—
ProductHCID 178480340HCID 178480340—

Reaction Steps

The title compound was prepared from 5,6-difluoro-2,3-dihydro-3-imino-1H-isoindol-1-one and 2-amino-N-(4-cyano-1-methyl-piperidin-4-yl)-3-cyclohexyl-propionamide bis hydrochloride salt according to the procedure from Example 86. MS, m/z 458.3=M+1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06420364B1
Source datasetuspto-grants-2002_07
ORD IDord-0d7269da674c4bb98ce28443a8300794
Source noteuspto-grants-2002_07