HCID 18467100, compound → HCID 18467087, compound

Participants

Reaction Steps

A suspension of N-[1-butyl-4-(3-methoxyphenyl)-1,2-dihydro-2-oxo-1,8-naphthyridin-3-yl]-N′-(2,6-diisopropyl-4-tritylaminophenyl)urea (273 mg, 0.348 mmol), a 10% palladium carbon (56 mg) in ethanol is stirred under hydrogen atmosphere at room temperature for 8 hours. The mixture is filtered on celite, and the solvent is concentrated under reduced pressure. The residue is purified by silica gel column chromatography to give the title compound (165 mg, 0.30 mmol) as crystals.

Provenance & Evidence