3-Aminobenzonitrile → 3-Aminobenzylamine

Participants

Reaction Steps

3-Cyanoaniline (0.50 g, 4.23 mmol) in 100 mL of MeOH was stirred overnight at room temperature under a H2 environment in the presence of 10% Pd/C (100 mg). The Pd/C was removed by filtration through a pad of Celilte, and the resulting filtrate was concentrated under reduced pressure to give 0.516 g (˜100%) of 44A as a thick oil. The product was used without any further purification.

Provenance & Evidence