HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → Cyclobuta[a]naphthalen-1(2H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 1,1-Diethoxy-1,2-dihydrocyclobuta[a]naphthalene | HCID 18467793 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | Cyclobuta[a]naphthalen-1(2H)-one | HCID 2752742 | 99.4% |
Reaction Steps
10 g of the product obtained in Step 1 are treated at room temperature with 42 ml of 1N hydrochloric acid dissolved in 170 ml of tetrahydrofuran. After 1 hour 30 minutes' contact, the solvent is concentrated and the residue is poured into 170 ml of water. 6.9 g of a solid corresponding to the expected product are then isolated.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06420413B2 |
| Source dataset | uspto-grants-2002_07 |
| ORD ID | ord-023f86ff8be245319bb8cec65fafc40f |
| Source note | uspto-grants-2002_07 |