HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tributylstannane → Acetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tributylstannane | HCID 5948 | — |
| Reactant | Heptane | HCID 8900 | — |
| Reactant | 2-Bromocyclohexanol | HCID 266411 | — |
| Reactant | 1-Hydroxy-4-benzoyloxy-2,2,6,6-tetramethylpiperidine | HCID 688178 | — |
| Solvent | Chlorobenzene | HCID 7964 | — |
| Product | Acetate | HCID 175 | — |
| Product | 4-Benzoyloxy-1-(2-hydroxycyclohexyloxy)-2,2,6,6-tetramethylpiperidine | HCID 22507645 | — |
Reaction Steps
Tributyltin hydride is added dropwise to a solution of 2-bromocyclohexanol and excess 4-benzoyloxy-1-oxyl-2,2,6,6-tetramethylpiperidine in chlorobenzene. The mixture is heated to facilitate reaction. The crude reaction mixture is passed through silica gel with heptane and then heptanelethyl acetate to afford the title compound as a mixture os cis/trans isomers.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06420562B2 |
| Source dataset | uspto-grants-2002_07 |
| ORD ID | ord-6aa6917e249f4f8ab932d7fb6c760d93 |
| Source note | uspto-grants-2002_07 |