HuagongsheHuagongshe Chemistry Print Report · For research reference only
Lithium Hydroxide → HCID 69463719, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Lithium Hydroxide | HCID 3939 | — |
| Reactant | N-tosyl-(s)-proline monohydrate | HCID 69463844 | — |
| Reactant | HCID 86758371 | HCID 86758371 | — |
| Solvent | Oxolane--water (1/1) | HCID 21881883 | — |
| Product | HCID 69463719 | HCID 69463719 | — |
Reaction Steps
N-(Toluene4-sulfonyl)-L-proline hydrate was coupled to β-tert-butyl L-aspartic acid methyl ester hydrochloride using the procedure described in Method 3. The title compound was prepared, via hydrolysis of the methyl ester using LiOH in THF/water, as a solid, mp=153-155° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06423688B1 |
| Source dataset | uspto-grants-2002_07 |
| ORD ID | ord-32e5dc5ffe1a4d6eb62541e765fffcf6 |
| Source note | uspto-grants-2002_07 |