HuagongsheHuagongshe Chemistry Print Report · For research reference only
Lithium Hydroxide → HCID 10368611, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Lithium Hydroxide | HCID 3939 | — |
| Reactant | L-Lysine, N6-[(1,1-dimethylethoxy)carbonyl]-, methyl ester, hydrochloride (1:1) | HCID 16218818 | — |
| Reactant | N-tosyl-(s)-proline monohydrate | HCID 69463844 | — |
| Solvent | Oxolane--water (1/1) | HCID 21881883 | — |
| Product | HCID 10368611 | HCID 10368611 | — |
Reaction Steps
N-(Toluene-4-sulfonyl)-L-proline hydrate was coupled to Nε-Boc-lysine methyl ester hydrochloride using the procedure described in Method 3. The title compound was prepared via hydrolysis of the methyl ester using LiOH in THF/water.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06423688B1 |
| Source dataset | uspto-grants-2002_07 |
| ORD ID | ord-c49407e181df470d982db94ce3b65cb5 |
| Source note | uspto-grants-2002_07 |