HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Nitrophenylboronic Acid → 6-(3-Nitro-phenyl)4-methyl-3,4-dihydro-1H-quinoxalin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Nitrophenylboronic Acid | HCID 1677 | — |
| Reactant | 6-Bromo-3,4-dihydro-4-methyl-2(1H)-quinoxalinone | HCID 22667740 | — |
| Product | 6-(3-Nitro-phenyl)4-methyl-3,4-dihydro-1H-quinoxalin-2-one | HCID 22667733 | — |
Reaction Steps
Prepared according to the procedure for Example 5 from 6-bromo-4-methyl-3,4-dihydro-1H-quinoxalin-2-one (4.8 g, 20 mmol), and 3-nitrophenylboronic acid (4.8 g, 30 mmol). A red powder (0.95 g, 16%): mp 237-243° C. 1H-NMR (DMSO-d6) δ 2.88 (s, 3H), 6.9 (d, J=7.9 Hz, 1H), 7.01 (d, J=2 Hz, 1H), 7.11 (dd, J=7.9, 2.0 Hz, 1H), 7.7 (t, J=7.9 Hz, 1H), 8.1 (m, 2H), 8.37 (t, J=0.7 Hz), MS (ESI) m/z 283 (M)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06423699B1 |
| Source dataset | uspto-grants-2002_07 |
| ORD ID | ord-372b73cb38a54f9b836aec8c2de93938 |
| Source note | uspto-grants-2002_07 |