3-(2-Methoxy-5-nitrophenoxy)-1-methylpyrrolidine → HCID 18180176, compound

HRID 2230112Notes

Reaction equation

HRID 2230112 reaction equation
[CH3:1][O:2][C:3]1[CH:15]=[CH:14][C:13]([N+:16]([O-])=O)=[CH:12][C:4]=1[O:5][CH:6]1[CH2:10][CH2:9][N:8]([CH3:11])[CH2:7]1>C(O)C.[Pd]>[CH3:1][O:2][C:3]1[CH:15]=[CH:14][C:13]([NH2:16])=[CH:12][C:4]=1[O:5][CH:6]1[CH2:10][CH2:9][N:8]([CH3:11])[CH2:7]1

Participants

4

Reactant 1

HCID 181801043-(2-Methoxy-5-nitrophenoxy)-1-methylpyrrolidine

Product 1

HCID 18180176HCID 18180176, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

A solution of 3-(2-methoxy-5-nitro-phenoxy)-1-methyl-pyrrolidine (3.0 g, 0.12 mmol) in ethanol (50 ml) was hydrogenated over 10% palladium on charcoal catalyst for 2 hrs to afford the title compound (D25). Found MH+ 223.

Sources & evidence

ORD record
ord-92fc0dc47d3e40158afd92747164467c
Source dataset
uspto-grants-2002_07
Patent number
US06423717B1

Reaction notes

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