HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 54162185, compound → HCID 54370100, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 54162185 | HCID 54162185 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 54370100 | HCID 54370100 | 99.5% |
Reaction Steps
A solution of (S)-1-methyl-2-(2-methoxy-5-nitrophenoxy)pyrrolidine (D43) (6.79 g; 0.0255 mol) in ethanol (200 ml) was hydrogenated in the presence of 5% Pd/C catalyst (0.5 g added as an aqueous slurry) at atmospheric pressure and RT for 16 hours. The catalyst was removed by filtration through kieselguhr and the filtrate evaporated in vacuo to yield the title compound (D44) (5.64 g; 93%) MH+=237.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06423717B1 |
| Source dataset | uspto-grants-2002_07 |
| ORD ID | ord-537d781cafb746bda675724a0b4b8138 |
| Source note | uspto-grants-2002_07 |