5-Chloro-3-methylbenzo(b)thiophene-2-sulfonyl chloride → HCID 18180119, compound

HRID 2230139Notes

Reaction equation

HRID 2230139 reaction equation
[Cl:1][C:2]1[CH:15]=[CH:14][C:5]2[S:6][C:7]([S:10](Cl)(=[O:12])=[O:11])=[C:8]([CH3:9])[C:4]=2[CH:3]=1.[CH3:16][C:17]1[CH:22]=[CH:21][C:20]([NH2:23])=[CH:19][C:18]=1[N:24]1[CH2:29][CH2:28][N:27]([CH3:30])[CH2:26][CH2:25]1>>[CH3:16][C:17]1[CH:22]=[CH:21][C:20]([NH:23][S:10]([C:7]2[S:6][C:5]3[CH:14]=[CH:15][C:2]([Cl:1])=[CH:3][C:4]=3[C:8]=2[CH3:9])(=[O:12])=[O:11])=[CH:19][C:18]=1[N:24]1[CH2:25][CH2:26][N:27]([CH3:30])[CH2:28][CH2:29]1

Participants

3

Reactant 2

HCID 27357565-Chloro-3-methylbenzo(b)thiophene-2-sulfonyl chlorideHCID 15541329HCID 15541329, compound

Product 1

HCID 18180119HCID 18180119, compound

Procedure

The title compound (E142) was prepared from 5-chloro-3-methylbenzo[b]thiophene-2-sulfonyl chloride and 4-methyl-3-(4-methylpiperazin-1-yl)benzenamine according to the method of Example 1 MH+32 448/450.

Sources & evidence

ORD record
ord-85d6fe4b2ee945bcbf0bef0d12b45b07
Source dataset
uspto-grants-2002_07
Patent number
US06423717B1

Reaction notes

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