HCID 12050337, compound → HCID 12050321, compound

HRID 2230168Notes

Reaction equation

HRID 2230168 reaction equation
[CH3:1][C:2]([CH3:21])([N:5]1[CH2:10][CH2:9][CH:8]([N:11]2[C:15]3[CH:16]=[CH:17][CH:18]=[CH:19][C:14]=3[NH:13][C:12]2=[O:20])[CH2:7][CH2:6]1)[C:3]#N.[C:22]1([Mg]Br)[CH:27]=[CH:26]C=[CH:24][CH:23]=1>>[CH3:1][C:2]([N:5]1[CH2:6][CH2:7][CH:8]([N:11]2[C:15]3[CH:16]=[CH:17][CH:18]=[CH:19][C:14]=3[NH:13][C:12]2=[O:20])[CH2:9][CH2:10]1)([C:3]1[CH:26]=[CH:27][CH:22]=[CH:23][CH:24]=1)[CH3:21]

Participants

3

Reactant 2

HCID 12050337HCID 12050337, compoundHCID 178418255HCID 178418255, compound

Product 1

HCID 12050321HCID 12050321, compoundYield 59%

Procedure

This was prepared according to the procedure described in Example 1 using 2,2-dimethyl-2-[4-(2-keto-1-benzimidazolinyl)piperidinyl]acetonitrile and phenylmagnesium bromide. Yield was 59%.

Workup

  1. customThis was prepared

Sources & evidence

ORD record
ord-e0223f478edb4465a15ec219c49856c5
Source dataset
uspto-grants-2002_07
Patent number
US06423725B1

Reaction notes

Loading…