HCID 11439171, compound → HCID 9821733, compound

HRID 2230169Notes

Reaction equation

HRID 2230169 reaction equation
[C:1]1([Mg]Br)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[O:9]=[C:10]1[N:14]([CH:15]2[CH2:20][CH2:19][N:18]([C:21]3(C#N)[CH2:27][CH2:26][CH2:25][CH2:24][CH2:23][CH2:22]3)[CH2:17][CH2:16]2)[C:13]2[CH:30]=[CH:31][CH:32]=[CH:33][C:12]=2[NH:11]1>>[C:1]1([C:21]2([N:18]3[CH2:19][CH2:20][CH:15]([N:14]4[C:13]5[CH:30]=[CH:31][CH:32]=[CH:33][C:12]=5[NH:11][C:10]4=[O:9])[CH2:16][CH2:17]3)[CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

3

Reactant 2

HCID 11439171HCID 11439171, compoundHCID 178418255HCID 178418255, compound

Product 1

HCID 9821733HCID 9821733, compoundYield 56%

Procedure

This was prepared according to the procedure described in Example 1 using phenylmagnesium bromide and 1-[4-(2-oxo-2,3-dihydro-1H-1,3-benzimidazol-1-yl)piperidino]-1-cycloheptanecarbonitrile. Yield was 56%.

Workup

  1. customThis was prepared

Sources & evidence

ORD record
ord-9dff913bb018490a9826a225e7ee662c
Source dataset
uspto-grants-2002_07
Patent number
US06423725B1

Reaction notes

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