HCID 18465391, compound → HCID 70107607, compound

HRID 2230170Notes

Reaction equation

HRID 2230170 reaction equation
[CH2:1]([C:3](C#N)([N:6]1[CH2:11][CH2:10][CH:9]([N:12]2[C:16]3[CH:17]=[CH:18][CH:19]=[CH:20][C:15]=3[NH:14][C:13]2=[O:21])[CH2:8][CH2:7]1)[CH2:4][CH3:5])[CH3:2].[C:24]1([Mg]Br)[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1>>[CH2:1]([C:3]([N:6]1[CH2:7][CH2:8][CH:9]([N:12]2[C:16]3[CH:17]=[CH:18][CH:19]=[CH:20][C:15]=3[NH:14][C:13]2=[O:21])[CH2:10][CH2:11]1)([C:24]1[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1)[CH2:4][CH3:5])[CH3:2]

Participants

3

Reactant 2

HCID 18465391HCID 18465391, compoundHCID 178418255HCID 178418255, compound

Product 1

HCID 70107607HCID 70107607, compoundYield 62%

Procedure

This was prepared according to the procedure described in Example 1 using 1-ethyl-1-[4-(2-oxo-2,3-dihydro-1H-1,3-benzimidazol-1-yl)piperidino]-propyl cyanide and phenylmagnesium bromide. Yield was 62%.

Workup

  1. customThis was prepared

Sources & evidence

ORD record
ord-28180d7d3d464f46816d757230901d20
Source dataset
uspto-grants-2002_07
Patent number
US06423725B1

Reaction notes

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