4-Nitro-o-anisic acid → HCID 18465928, compound

HRID 2230248Notes

Reaction equation

HRID 2230248 reaction equation
[N+:1]([CH2:3][C:4]([O:6][CH3:7])=[O:5])#[C-:2].[CH3:8][O:9][C:10]1[CH:18]=[C:17]([N+:19]([O-:21])=[O:20])[CH:16]=[CH:15][C:11]=1[C:12](O)=[O:13]>>[CH3:8][O:9][C:10]1[CH:18]=[C:17]([N+:19]([O-:21])=[O:20])[CH:16]=[CH:15][C:11]=1[C:12]1[O:13][CH:2]=[N:1][C:3]=1[C:4]([O:6][CH3:7])=[O:5]

Participants

3

Reactant 2

HCID 757764-Nitro-o-anisic acidHCID 547815Methyl isocyanoacetate

Product 1

HCID 18465928HCID 18465928, compound

Procedure

The procedures of Example 1-(1) were followed, except for replacing the ethyl isocyanoacetate with 9.9 g (0.1 mol) of methyl isocyanoacetate, to obtain 15.4 g (0.055 mol 61.5% based on the 2-methoxy-4-nitrobenzoic acid) of the title compound.

Workup

  1. customto obtain 15.4 g (0.055 mol 61.5%

Sources & evidence

ORD record
ord-a8d9477b5b5a4fa9bb7e9f7a5f246251
Source dataset
uspto-grants-2002_07
Patent number
US06423849B1

Reaction notes

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