(2S)-2-(azepane-1-carbonylamino)-4-methylpentanoic acid → HCID 70058605, compound

HRID 2230310Notes

Reaction equation

HRID 2230310 reaction equation
[C:1]([O:5][C:6](=[O:24])[C@@H:7]([NH2:23])[CH2:8][C:9]1[CH:14]=[CH:13][C:12]([O:15][CH2:16][C:17]2[CH:22]=[CH:21][N:20]=[CH:19][CH:18]=2)=[CH:11][CH:10]=1)([CH3:4])([CH3:3])[CH3:2].[N:25]1([C:32]([NH:34][C@@H:35]([CH2:39][CH:40]([CH3:42])[CH3:41])[C:36](O)=[O:37])=[O:33])[CH2:31][CH2:30][CH2:29][CH2:28][CH2:27][CH2:26]1>>[C:1]([O:5][C:6](=[O:24])[CH:7]([NH:23][C:36](=[O:37])[CH:35]([NH:34][C:32]([N:25]1[CH2:31][CH2:30][CH2:29][CH2:28][CH2:27][CH2:26]1)=[O:33])[CH2:39][CH:40]([CH3:42])[CH3:41])[CH2:8][C:9]1[CH:14]=[CH:13][C:12]([O:15][CH2:16][C:17]2[CH:22]=[CH:21][N:20]=[CH:19][CH:18]=2)=[CH:11][CH:10]=1)([CH3:4])([CH3:2])[CH3:3]

Participants

3

Reactant 2

HCID 7530182(2S)-2-(azepane-1-carbonylamino)-4-methylpentanoic acidHCID 70060268HCID 70060268, compound

Product 1

HCID 70058605HCID 70058605, compound

Procedure

In a manner similar to that described in Example 25, the product from Example O and the product from Example Z were coupled to give the title compound.

Sources & evidence

ORD record
ord-eda3c9bd74fe461f81fb428f2c588f84
Source dataset
uspto-grants-2002_07
Patent number
US06423689B1

Reaction notes

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