(2S)-2-(azepane-1-carbonylamino)-4-methylpentanoic acid → HCID 70060077, compound

HRID 2230311Notes

Reaction equation

HRID 2230311 reaction equation
[C:1]([O:5][C:6](=[O:32])[C@@H:7]([NH2:31])[CH2:8][C:9]1[CH:14]=[CH:13][C:12]([O:15][CH2:16][C:17]2[CH:22]=[CH:21][CH:20]=[C:19]([NH:23][C:24]([O:26][C:27]([CH3:30])([CH3:29])[CH3:28])=[O:25])[CH:18]=2)=[CH:11][CH:10]=1)([CH3:4])([CH3:3])[CH3:2].[N:33]1([C:40]([NH:42][C@@H:43]([CH2:47][CH:48]([CH3:50])[CH3:49])[C:44](O)=[O:45])=[O:41])[CH2:39][CH2:38][CH2:37][CH2:36][CH2:35][CH2:34]1>>[C:1]([O:5][C:6](=[O:32])[CH:7]([NH:31][C:44](=[O:45])[CH:43]([NH:42][C:40]([N:33]1[CH2:39][CH2:38][CH2:37][CH2:36][CH2:35][CH2:34]1)=[O:41])[CH2:47][CH:48]([CH3:50])[CH3:49])[CH2:8][C:9]1[CH:10]=[CH:11][C:12]([O:15][CH2:16][C:17]2[CH:22]=[CH:21][CH:20]=[C:19]([NH:23][C:24]([O:26][C:27]([CH3:30])([CH3:29])[CH3:28])=[O:25])[CH:18]=2)=[CH:13][CH:14]=1)([CH3:3])([CH3:2])[CH3:4]

Participants

3

Reactant 2

HCID 7530182(2S)-2-(azepane-1-carbonylamino)-4-methylpentanoic acidHCID 70060224HCID 70060224, compound

Product 1

HCID 70060077HCID 70060077, compound

Procedure

In a manner similar to that described in Example 25, the product from Example Q and the product from Example Z were coupled to give the title compound.

Sources & evidence

ORD record
ord-f04cf4690cee40f3bbdf6ab6b91e9384
Source dataset
uspto-grants-2002_07
Patent number
US06423689B1

Reaction notes

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