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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2230354Generated: November 2, 2026

HCID 178505591, compound → HCID 178505595, compound

https://huagongshe.com/reaction/2230354

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 178505591HCID 178505591—
SolventBenzylamineHCID 7504—
ProductHCID 178505595HCID 17850559595%

Reaction Steps

This compound was synthesize by refluxing 2-chloro-4-[3-(4-fluorophenyl)-1H-pyrazol-4-yl]pyrimidine prepared in accordance with Example A-299 in benzylamine overnight. The product, 4-[3-(4-fluorophenyl)-1H -pyrazol-4-yl]-N-(phenylmethyl)-2-pyrimidinamine, was obtained as a white solid in 95% yield; mp: 216-217° C.; Anal. Calc'd for C20H16FN5: C, 69.55; H, 4.67; N, 20.28. Found: C, 69.73; H, 4.69; N, 19.90.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06423713B1
Source datasetuspto-grants-2002_07
ORD IDord-9b7da064d76245eea708e24cae7821bf
Source noteuspto-grants-2002_07