HCID 57114159, compound → HCID 59902680, compound

Participants

Reaction Steps

Diphenylmethyl (2S,3R,4R,5S)-2,3,4,6-tetraacetoxy-5-(N-benzyloxycarbonyl-L-leucyl)aminohexanoate (270 mg) was dissolved in trifluoroacetic acid (5 ml) and the solution was stirred at room temperature for 1 hour. After concentration under reduced pressure, the residue was passed through silica gel column chromatography, followed by elution with ethyl acetate-methanol (10:1). The effective fractions were combined and concent rated under reduced pressure to afford the title compound (214 mg).

Provenance & Evidence