Hydrochloric Acid → HCID 59902678, compound

Participants

Reaction Steps

To diphenylmethyl (S)-3-[(2S,3R,4R,5S)-5-(O-tert-butyl-L-seryl)amino-2,3,4,6-tetrahydroxyhexanoyl]amino-3-phenylpropionate (300 mg) was added 4N hydrogen chloride solution in ethyl acetate (10 ml) and the mixture was stirred at room temperature for 1.5 hours. Removal of the organic solvent gave a residue, which was extracted with water. The aqueous layer was washed with diethylether and concentrated under reduced pressure. The residue was recrystallized from methanol-diethylether to afford the title compound (208 mg).

Provenance & Evidence