Potassium Bromide → HCID 18465727, compound

Participants

Reaction Steps

was synthesized from 215c by the same method as compound 216e as a glassy white solid (300 mg, 83%): mp 80-125° C.; [α]D23 −89.1 (c 1.08, CH2Cl2); IR (KBr) 3356, 2979, 2935, 1740, 1659, 1532, 1434, 1369, 1276, 1260, 1151; 1H NMR (CDCl3) δ7.39-7.32 (3H, m), 7.13 (1H, d), 6.34 (1H, d), 5.22-5.17 (1H, m), 5.11 (1H, d), 5.04 (1H, d), 4.99-4.88 (2H, m), 4.64-4.52 (1H, m), 3.29-3.11 (1H, m), 3.05-2.67 (4H, m), 2.39-2.29 (1H, m), 2.02 (3H, s), 1.98-1.75 (4H, m), 1.46 (9H, s); Anal. Calcd for C28H34N4Cl2O9: C, 52.42; H, 5.34; N, 8.73. Found: C, 52.53; H, 5.70; N, 7.85. MS (ES−) 643/41/39 (M−1, 100%). Accurate mass calculated for C28H35N4Cl2O9 (MH+): 641.1781. Found: 641.1735. Accurate mass calculated for C28H34N4Cl2O9Na (Mna+): 663.1601. Found: 663.1542.

Provenance & Evidence