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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2230543Generated: October 30, 2026

3-(Chloromethyl)furan → HCID 18464816, compound

https://huagongshe.com/reaction/2230543

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(Chloromethyl)furanHCID 11126228—
Reactant1-(3,4,5-trimethoxybenzoyl)-3-(2-(4-(1H-benzimidazol-2-yl)[1,4]diazepan-1-yl)ethyl)-3-phenylpyrrolidineHCID 18464478—
ProductHCID 18464816HCID 18464816—

Reaction Steps

Prepare by the method of Example 35.1 using 1-(3,4,5-trimethoxybenzoyl)-3-(2-(4-(1H-benzimidazol-2-yl)[1,4]diazepan-1-yl)ethyl)-3-phenylpyrrolidine (prepared from (−)-3-phenyl-3-(2-hydroxyethyl)pyrrolidine (R,R)-di-p-anisoyltartaric acid salt) and 3-(chloromethyl)furan (J. Am. Chem. Soc. 72, 2195-2199 (1950)) to give the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06423704B1
Source datasetuspto-grants-2002_07
ORD IDord-22e482a827074f5f90ee4dd17931c75a
Source noteuspto-grants-2002_07