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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2230545Generated: October 30, 2026

1-Bromo-2-butanone → HCID 18464754, compound

https://huagongshe.com/reaction/2230545

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Bromo-2-butanoneHCID 13156—
Reactant1-(3,4,5-trimethoxybenzoyl)-3-(2-(4-(1H-benzimidazol-2-yl)[1,4]diazepan-1-yl)ethyl)-3-phenylpyrrolidineHCID 18464478—
ProductHCID 18464754HCID 18464754—

Reaction Steps

Prepare by the method of Example 35.1 using 1-(3,4,5-trimethoxybenzoyl)-3-(2-(4-(1H-benzimidazol-2-yl)[1,4]diazepan-1-yl)ethyl)-3-phenylpyrrolidine (prepared from (−)-3-phenyl-3-(2-hydroxyethyl)pyrrolidine (R,R)-di-p-anisoyltartaric acid salt) and 1-bromo-butan-2-one to give the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06423704B1
Source datasetuspto-grants-2002_07
ORD IDord-f9c7ff8d293a4bc2825c6ceca59f7e01
Source noteuspto-grants-2002_07