HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Acid → 2-Methylsulfonyl-5-(1H-tetrazol-1-yl)benzoic Acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Acid | HCID 176 | — |
| Reactant | Hydrogen Peroxide | HCID 784 | — |
| Reactant | Water | HCID 962 | — |
| Reactant | 2-Methylthio-5-(1H-tetrazol-1-yl)benzoic Acid | HCID 18464518 | — |
| Product | 2-Methylsulfonyl-5-(1H-tetrazol-1-yl)benzoic Acid | HCID 18464865 | — |
Reaction Conditions
| Temperature | 100 °C |
|---|
Reaction Steps
Combine 2-methylthio-5-(1H-tetrazol-1-yl)benzoic acid (0.68 g, 0.29 mmol), 30% hydrogen peroxide (3 ml.) and glacial acetic acid (20 mL). After 2 hours, heat to 100° C. After 2 hours, cool to ambient temperature and add water (250 mL) to give a solid. Collect the solid by filtration and dry to give the title compound: Rf=0.21 (silica gel, 10% methanol/85% dichloromethane/5% acetic acid).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06423704B1 |
| Source dataset | uspto-grants-2002_07 |
| ORD ID | ord-543b40388a6e402e8d711646918accaa |
| Source note | uspto-grants-2002_07 |