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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2230659Generated: October 31, 2026

5-Fluoro-2-methoxybenzoic acid → HCID 18464807, compound

https://huagongshe.com/reaction/2230659

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Fluoro-2-methoxybenzoic acidHCID 2737364—
Reactant3-(2-(4-(1-(2-ethoxyethyl)-1H-benzimidazol-2-yl)[1,4]diazepan-1-yl)ethyl)-3-phenylpyrrolidine hydrochloric acidHCID 18464957—
ProductHCID 18464807HCID 18464807—

Reaction Steps

Prepare by the method of Example 56.1 using 2-methoxy-5-fluorobenzoic acid and 3-(2-(4-(1-(2-ethoxyethyl)-1H-benzimidazol-2-yl)[1,4]diazepan-1-yl)ethyl)-3-phenylpyrrolidine hydrochloric acid salt (prepared from (−)-3-phenyl-3-(2-hydroxyethyl)pyrrolidine (R,R)-di-p-anisoyltartaric acid salt) to give the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06423704B1
Source datasetuspto-grants-2002_07
ORD IDord-c63dd1fca59042aab30471675855acfb
Source noteuspto-grants-2002_07