Maleic Anhydride → 826-62-0
Reaction equation
C1(=O)OC(=O)C=C1.N1(CC[C:16]2([C:34]([O-:36])=[O:35])[C:21](CCN3CCOCC3)([C:22]([O-:24])=O)[CH:20]3[CH2:33][CH:17]2[CH:18]=[CH:19]3)CCOCC1>>[CH:20]12[CH2:33][CH:17]([CH:18]=[CH:19]1)[CH:16]1[C:34]([O:36][C:22](=[O:24])[CH:21]21)=[O:35]Participants
3
Procedure
More specifically, in the step (a2) above, compound 2 is dissolved in an organic solvent and cooled at temperature in the range of from about −35° C. to about −25° C. Maleic anhydride, preferably in a solution and in an equal amount, is slowly added to the resulting solution. The reaction mixture is then stirred for about 8 to 12 hours at temperature in the range of from about −35° C. to about −25° C. After which the reaction temperature is allowed to reach room temperature. The reaction mixture is stirred for additional about 8 to 12 hours, and the 5-norbornene-2,3-dicarboxylic anhydride is obtained after removing the organic solvent.
Workup
- temperaturecooled at temperature in the range of from about −35° C. to about −25° C
- customto reach room temperature
- stirringThe reaction mixture is stirred for additional about 8 to 12 hours
Sources & evidence
- ORD record
- ord-88881490bfd540769150c3e9e26bb950
- Source dataset
- uspto-grants-2002_07
- Patent number
- US06426171B1
Reaction notes
Loading…