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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2230896Generated: October 30, 2026

1-(4-Fluorophenyl)-2-methylpropan-1-ol → 1-(4-Fluorophenyl)-2-methylpropan-1-one

https://huagongshe.com/reaction/2230896

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(4-Fluorophenyl)-2-methylpropan-1-olHCID 10419564—
ReactantJones' reagentHCID 131709961—
SolventAcetoneHCID 180—
Product1-(4-Fluorophenyl)-2-methylpropan-1-oneHCID 2782829—

Reaction Steps

To a solution of 1-(4-Fluoro-phenyl)-2-methyl-propan-1-ol (1.6 g) in acetone (10 mL) at 0° C. is added Jones reagent (20 mL) with stirring. After 10 minutes excess Jones reagent is destroyed by addition of isopropyl alcohol. Diethyl ether is added followed by anhydrous magnesium and the mixture is filtered and evaporated to give the product, a yellow oil (1.2 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06426355B1
Source datasetuspto-grants-2002_07
ORD IDord-ac4dd771d6634215bc2b55c7330a6007
Source noteuspto-grants-2002_07