Hesperetin-7-Rutinoside → Diosmin

HRID 2230904Notes

Reaction equation

[CH3:1][C@@H:2]1[O:7][C@@H:6]([O:8][CH2:9][C@H:10]2[O:15][C@@H:14]([O:16][C:17]3[CH:18]=[C:19]([OH:37])[C:20]4[C:26](=[O:27])[CH2:25][C@@H:24]([C:28]5[CH:29]=[CH:30][C:31]([O:35][CH3:36])=[C:32]([OH:34])[CH:33]=5)[O:23][C:21]=4[CH:22]=3)[C@H:13]([OH:38])[C@@H:12]([OH:39])[C@@H:11]2[OH:40])[C@H:5]([OH:41])[C@H:4]([OH:42])[C@H:3]1[OH:43].CC1OC(OCC2OC(OC3C=C4C(C(CC(C5C=CC(OC)=C(O)C=5)O4)=O)=C(O)C=3)C(O)C(O)C2O)C(O)C(O)C1O>>[CH3:1][C@@H:2]1[O:7][C@@H:6]([O:8][CH2:9][C@H:10]2[O:15][C@@H:14]([O:16][C:17]3[CH:18]=[C:19]([OH:37])[C:20]4[C:26](=[O:27])[CH:25]=[C:24]([C:28]5[CH:29]=[CH:30][C:31]([O:35][CH3:36])=[C:32]([OH:34])[CH:33]=5)[O:23][C:21]=4[CH:22]=3)[C@H:13]([OH:38])[C@@H:12]([OH:39])[C@@H:11]2[OH:40])[C@H:5]([OH:41])[C@H:4]([OH:42])[C@H:3]1[OH:43]

Participants

Reactant 2

HCID 3594Hesperetin-7-Rutinoside2×

HCID 10621Hesperidin3×

Product 1

HCID 5281613Diosmin

Procedure

hesperidin, (S)-7-[[6-O-(6-Deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one; hesperetin 7-rhamnoglucoside; cirantin; hesperetin-7-rutinoside;

Sources & evidence

ORD record: ord-f12a282c4e954fec85a45546cfbbc23c
Source dataset: uspto-grants-2002_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06426362B1

Reaction notes

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