HCID 20522503, compound → L-Alanine, N-acetyl-L-phenylalanyl-

Participants

Reaction Steps

According to the same procedure as in Example 1, 1-(1-methoxycarbonylethyl)-3-acetylamino-4-phenylazetidin-2-one (400 mg.) was subjected to hydrogenolysis at 50° C. in ethanol (30 ml.) under a hydrogen pressure of one atmosphere in the presence of a 10% Pd-C (580 mg.). The reaction was completed in 7 hours. The same after-treatment as in Example 1 was followed to give methyl ester of N-acetylphenylalanylalanine (390 mg., yield: 96.8%) melting at 147.0°-155.0° C.

Provenance & Evidence