HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → HCID 22724408, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 2-Chloro-3-nitropyridine | HCID 79613 | — |
| Reactant | 3-(2-Pyridyl)aniline | HCID 459517 | — |
| Solvent | Diglyme | HCID 8150 | — |
| Product | HCID 22724408 | HCID 22724408 | 87.3% |
Reaction Conditions
| Temperature | 150 °C |
|---|
Reaction Steps
A mixture of 2-chloro-3-nitropyridine (1.15 g), 2-(3-aminophenyl)pyridine (1.12 g) and potassium carbonate (1.36 g) in diglyme (15 ml) was stirred at 150° C. for 3 hours. After cooling, insoluble materials were removed by filtration and the filtrate was concentrated. The residue was chromatographed on silica gel column (hexane-ethyl acetate, 1:1) to give 3-nitro-2-[3-(2-pyridyl)phenylamino]pyridine (1.68 g)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06426345B1 |
| Source dataset | uspto-grants-2002_07 |
| ORD ID | ord-c91bcf9d5dc54943a76ae980140f0d35 |
| Source note | uspto-grants-2002_07 |