HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → H-D-Phe-Ala-OH
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | 1-(1(S)-t-butoxycarbonylethyl)-3(R)-azido-4(S)-phenylazetidin-2-one | HCID 13035215 | — |
| Product | H-D-Phe-Ala-OH | HCID 6993122 | 140.8% |
Reaction Steps
According to the same procedure as in Example 15 except that 1-(1(S)-t-butoxycarbonylethyl)-3(R)-azido-4(S)-phenylazetidin-2-one (300 mg., 0.95 mmol) was used as a starting material, trifluoroacetic acid salt of D-phenylalanyl-L-alanine (316 mg., yield: 95%) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04352752 |
| Source dataset | uspto-grants-1982_10 |
| ORD ID | ord-6ba22c4ffe3d4cb188eceb4e96ce8e4a |
| Source note | uspto-grants-1982_10 |