Methyl iodide → HCID 13823248, compound

Participants

Reaction Steps

1 g of 2-[3,5-dichloro-4-(4-methylsulfonylphenoxy)phenyl]hexahydro-1,2,4-triazine-3,5-dione was dissolved in 10 ml of dimethylformamide and, with exclusion of moisture, about 250 mg of a suspension of sodium hydride were added. After the evolution of gases was complete, 1 ml of methyl iodide was added, with stirring, and then the mixture was stirred at room temperature for a further 5 h. The reaction solution was poured onto water, and the precipitate was filtered off with suction and recrystallized from isopropanol, melting point 217° C.

Provenance & Evidence