N-Phenyl-o-phenylenediamine → 2-methyl-1-phenyl-1H-benzimidazole

Participants

Reaction Steps

A solution of 10 g (0.054, mole) of N-phenyl-1,2phenylenediamine and 9.94 ml (0.054 mole) of triethylorthoacetate in 200 ml of ethanol was heated to reflux for 4 hours. The solvent was removed and the residue partitioned between chloroform and water. The organic layer was separated, dried and removed to give 11.99 g of product as an oil.

Provenance & Evidence