Sodium Thiosulfate → HCID 14390549, compound

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A mixture of 2-(2,2-dichloroethenyl)-5-(4-methylsulfinylphenyl)thiophene (0.8 g, 0.0025 mole) and m-chloroperbenzoic acid (2.0 g, 0.005 mole) in methylene chloride (50 mL) was stirred at room temperature for two days. The mixture was poured into a 0.5N aqueous sodium thiosulfate solution. The resultant mixture was extracted with diethyl ether. The extract was washed first with an aqueous 10% sodium hydroxide solution, followed by an aqueous 10% hydrochloric acid solution. The washed extract was dried over anhydrous magnesium sulfate and filtered. The filtrate was evaporated under reduced pressure, leaving a solid residue. This residue was purified by column chromatography on alumina, eluting with n-hexane:ethyl acetate (50:50), yielding 0.4 g of 2-(2,2-dichloroethenyl)-5-(4-methylsulfonylphenyl)thiophene as a solid (mp 143°-145° C.).

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